Will Viagra work with Low My Testosterone?

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Viagra is one of the most popular supplements among men, and you don’t even need to be an older adult to need an extra boost to your self-confidence. Viagra is used by anyone who’s having erection problems, and it seems to be an excellent solution without any adverse effects to worry about. There’s even a female version of Viagra, but it is not so quick and effective as male’s Viagra and works in the central nervous system instead of directly changing the way things work down there in the erogenous zones.

On the other hand, low testosterone levels become more common as we grow older, but it may happen to young adults as well. One of the signs that create more frustration among men with low testosterone levels is impotence, a difficulty to achieve hard and long-lasting erections. That’s why many adult males with low testosterone who are about to try Viagra may become worried about whether or not it will work for them. Do they need a special dose to make up for their lack of testosterone?

 

Low testosterone, libido, and achieving sexual potency

Some men have extremely low Testosterone. Testosterone is a steroid hormone with complex reactions across the body. It interacts with almost every tissue in the human body and modulates the activity and function of each one of them in a different way. No wonder why low testosterone levels are associated with many signs and symptoms, including low libido and sexual impotence.

Testosterone is mainly synthesized and secreted by the male’s testis and the organs of the reproductive system count as the main targets of this hormone. Testosterone modulates the external appearance of the genitalia, the size, and thickness of the penis, and the sexual function during intercourse. Moreover, it triggers brain functions that increase sexual desire and arousal, which ultimately promotes that big and hard erection most of us are looking for.

 

Viagra and Testosterone Research

with thanks www.ncbi.nlm.nih.gov

 

To promote erections, testosterone needs to be metabolized into an active androgenic steroid and then bind to receptors in brain cells located in the preoptic area and other key sites. After coupling with the receptors, testosterone starts to modulate gene transcription and changes the way brain cells work, making them more excitable and ready for sexual arousal. This process is not fast and takes many hours and even days to develop.

Thus, we can’t say testosterone will help you trigger an immediate erection. Instead, it lays the foundations to make it easier for your body. Sexual behavior is a very complex topic where many different pieces come into play, and testosterone is just one of them. Further, as you could see, testosterone is not directly linked to your capacity of achieving an erection, and even if low testosterone is known to cause impotence, it is not because of a direct dysfunction in the ability of your penis to get filled with blood.

 

Viagra: How it works and what it does

So how does Sildenafil or Viagra actually work?  Viagra is a popular drug used to treat erectile dysfunction, and it was initially thought as an agent to improve blood circulation with a side effect that turned out to become its source of popularity. What Viagra does to promote erections is not associated with the brain tissue but the blood circulation in your penis.

Sildenafil inhibits an enzyme that modulates the way blood moves in and out of the penis. An erection is fully achieved when the blood is filling the soft tissue of the penis, and when you use Viagra the main effect is a dilation of your penis because more blood flow is allowed to enter and fill the soft tissue.

Viagra does not change how your brain works in any way. Its effects are limited to improving the blood flow to your genitalia and may also reduce your refractory period (the time you need to recover after reaching an orgasm), and other reported effects such as increase in sexual drive or making you last longer in bed simply result from an increase in sexual confidence and improved sense of control over your own sexuality.

 

 

Is there a link between LOW testosterone and efficacy of Viagra?

As stated in the corresponding sections about testosterone and Viagra, each one of them works differently to achieve the same goal. Thus, most people would reach the reasonable conclusion that Viagra works for people with low and high levels of testosterone alike. However, not everything is as it seems when it comes to the human body and its countless interactions.

Studies have reported that testosterone appears to improve your individual responsiveness to sildenafil. The reason for this effect might be related to a substance called nitric oxide, a potent vasodilator substance that works in the blood vessels throughout the body, including those in the soft tissue of the penis. Testosterone favors the synthesis and secretion of nitric oxide, which mainly has cardiovascular implications such as lower levels of blood pressure and improved endothelial function, but it is also associated with the ability to reach and maintain erections.

Patients with low levels of testosterone may or may not experience a failure when trying to achieve an erection with Viagra. It depends on a variety of anatomical and chemical variations in each organism, especially when it comes to nitric oxide production, which is further modulated by exercise, diet, antioxidants, and much more.

What doctors usually do in these cases is not increasing the dose of Viagra because it is working as it should. Instead, it will be necessary to implement a testosterone replacement therapy to get back to normal levels of testosterone in the blood. This can be achieved by using testosterone shots, transdermal applications, and many other options laid down for patients with low circulating levels of testosterone.

References:

Balthazart, J., & Ball, G. F. (2018). Sexual Behavior in Males From a Neuroendocrine Perspective. In Oxford Research Encyclopedia of Neuroscience.

 

Charlier, T. D., Seredynski, A. L., Niessen, N. A., & Balthazart, J. (2013). Modulation of testosterone-dependent male sexual behavior and the associated neuroplasticity. General and comparative endocrinology, 190, 24-33.

 

Reddy, M. S., & Vijay, M. S. (2017). Pharmacological advances in the management of sexual dysfunction. Indian journal of psychological medicine, 39(3), 219.

 

Morley, J. E., & Perry III, H. M. (1999). Androgen deficiency in aging men. Medical Clinics of North America, 83(5), 1279-1289.

 

Rosenthal, B. D., May, N. R., Metro, M. J., Harkaway, R. C., & Ginsberg, P. C. (2006). Adjunctive use of AndroGel (testosterone gel) with sildenafil to treat erectile dysfunction in men with acquired androgen deficiency syndrome after failure using sildenafil alone. Urology, 67(3), 571-574.

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